The Magnotta Lab is currently focusing on the development of quantitative magnetic resonance imaging techniques that are sensitive to brain metabolism. Currently we are focusing on T1rho, CEST, and MR spectroscopic based techniques. Using these techniques coupled with other quantitative imaging markers (e.g. T1 and T2 relaxation measures) we are exploring metabolic changes associated with several psychiatric (schizophrenia, bipolar disorder) and neurological disorders (Huntington’s disease, Alzheimer’s disease). In addition, we are exploring how metabolism changes with symptoms and disease progression. Future work will accelerate these imaging measures allowing them to assess functional changes in the brain.